Key takeaways
- Lisinopril is an ACE inhibitor, while losartan is an angiotensin II receptor blocker (ARB).
- Both require an individual review of health history, current medicines, measurements, and monitoring needs.
- They are not interchangeable, and a patient should not switch or combine them without prescriber guidance.
How they compare
EDITORIAL GUIDETopicLisinoprillisinoprilLosartanlosartan potassium
Medication familyACE inhibitorAngiotensin II receptor blocker (ARB)
Common discussionBlood-pressure and selected heart or kidney care plansBlood-pressure and selected heart or kidney care plans
Product formOral tabletOral tablet
AccessPrescription requiredPrescription required
DecisionRequires an individual clinician reviewRequires an individual clinician review
Primary sources
Labeling can change. Use the current FDA prescribing information and speak with a licensed clinician or pharmacist before making a treatment decision.