Key takeaways
- Valacyclovir is converted to acyclovir in the body, but the products and dosing instructions are not interchangeable.
- The diagnosis, timing, kidney function, other medicines, and episodic-versus-suppressive goal affect the plan.
- Use the exact prescribed medicine, strength, schedule, and duration rather than converting between products yourself.
How they compare
EDITORIAL GUIDETopicValacyclovirvalacyclovir hydrochlorideAcycloviracyclovir
Medication familyAntiviral; prodrug of acyclovirAntiviral nucleoside analogue
Common discussionSelected herpesvirus infections and care plansSelected herpesvirus infections and care plans
Product formOral tabletOral and topical product forms
AccessPrescription requiredPrescription required
DecisionRequires an individual clinician reviewRequires an individual clinician review
Primary sources
Labeling can change. Use the current FDA prescribing information and speak with a licensed clinician or pharmacist before making a treatment decision.