Key takeaways
- Both are prescription tirzepatide products that act on GIP and GLP-1 receptors.
- Zepbound is commonly discussed for chronic weight management, while Mounjaro is commonly discussed for type 2 diabetes.
- A clinician must review contraindications, other medicines, and the intended use before recommending either product.
How they compare
EDITORIAL GUIDETopicZepboundtirzepatideMounjarotirzepatide
Active ingredientTirzepatideTirzepatide
Medication classGIP/GLP-1 receptor agonistGIP/GLP-1 receptor agonist
Common FDA-approved focusChronic weight management for eligible patientsType 2 diabetes management for eligible patients
AccessPrescription requiredPrescription required
DecisionWeight history, risks, current medicines, and goals must be reviewedDiabetes history, risks, current medicines, and goals must be reviewed
Primary sources
Labeling can change. Use the current FDA prescribing information and speak with a licensed clinician or pharmacist before making a treatment decision.